Enhanced Gαq signaling: A common pathway mediates cardiac hypertrophy and apoptotic heart failure

Receptor-mediated Gq signaling promotes hypertrophic growth of cultured neonatal rat cardiac myocytes and is postulated to transduce in vivo cardiac pressure overload hypertrophy. Although initially compensatory, hypertrophy can proceed by unknown mechanisms to cardiac failure. We used adenoviral in...

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Hauptverfasser: Adams, John W., Sakata, Yoshihito, Davis, Michael G., Sah, Valerie P., Wang, Yibin, Liggett, Stephen B., Chien, Kenneth R., Brown, Joan Heller, Dorn, Gerald W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1998
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC21475/
https://ncbi.nlm.nih.gov/pubmed/9707614
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