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Cardiac-specific overexpression of RhoA results in sinus and atrioventricular nodal dysfunction and contractile failure

RhoA is a low-molecular-weight GTPase that has been implicated in the regulation of hypertrophic cardiac muscle cell growth. To study the role of RhoA in control of cardiac function in vivo, transgenic mice expressing wild-type and constitutively activated forms of RhoA under the control of the card...

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Detalhes bibliográficos
Main Authors: Sah, Valerie P., Minamisawa, Susumu, Tam, Steven P., Wu, Thomas H., Dorn, Gerald W., Ross, John, Chien, Kenneth R., Brown, Joan Heller
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC408391/
https://ncbi.nlm.nih.gov/pubmed/10377168
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