Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory

Subcortical dopamine D2 receptor (DRD2) signaling is implicated in cognitive processes and brain disorders, but the effect of DRD2 variants remains ambiguous. We measured allelic mRNA expression in postmortem human striatum and prefrontal cortex and then performed single nucleotide polymorphism (SNP...

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Detalhes bibliográficos
Main Authors: Zhang, Ying, Bertolino, Alessandro, Fazio, Leonardo, Blasi, Giuseppe, Rampino, Antonio, Romano, Raffaella, Lee, Mei-Ling T., Xiao, Tao, Papp, Audrey, Wang, Danxin, Sadée, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154469/
https://ncbi.nlm.nih.gov/pubmed/18077373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707106104
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