Polymorphisms in human dopamine D2 receptor gene affect gene expression, splicing, and neuronal activity during working memory

Subcortical dopamine D2 receptor (DRD2) signaling is implicated in cognitive processes and brain disorders, but the effect of DRD2 variants remains ambiguous. We measured allelic mRNA expression in postmortem human striatum and prefrontal cortex and then performed single nucleotide polymorphism (SNP...

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Hlavní autoři: Zhang, Ying, Bertolino, Alessandro, Fazio, Leonardo, Blasi, Giuseppe, Rampino, Antonio, Romano, Raffaella, Lee, Mei-Ling T., Xiao, Tao, Papp, Audrey, Wang, Danxin, Sadée, Wolfgang
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154469/
https://ncbi.nlm.nih.gov/pubmed/18077373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707106104
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