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Functional variants of the dopamine receptor D2 gene modulate prefronto-striatal phenotypes in schizophrenia
Dopamine D2 receptor signalling is strongly implicated in the aetiology of schizophrenia. We have recently characterized the function of three DRD2 SNPs: rs12364283 in the promoter affecting total D2 mRNA expression; rs2283265 and rs1076560, respectively in introns 5 and 6, shifting mRNA splicing to...
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| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2640212/ https://ncbi.nlm.nih.gov/pubmed/18829695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awn248 |
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