Kinetic theory of fibrillogenesis of amyloid β-protein

Prior quasielastic light scattering (QLS) studies of fibrillogenesis of synthetic amyloid β-protein (Aβ)-(1–40) at low pH have suggested a kinetic model in which: (i) fibrillogenesis requires a nucleation step; (ii) nuclei are produced by Aβ micelles in addition to seeds initially present; and (iii)...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Lomakin, Aleksey, Teplow, David B., Kirschner, Daniel A., Benedek, George B.
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21534/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9223292/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.15.7942
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