Variations in Reverse Transcriptase and RNase H Domain Mutations in Human Immunodeficiency Virus Type 1 Clinical Isolates Are Associated with Divergent Phenotypic Resistance to Zidovudine

Mutations in the RNase H domain of human immunodeficiency virus type 1 RT have been reported to cause resistance to zidovudine (ZDV) in vitro. However, very limited data on the in vivo relevance of these mutations in patients exist to date. This study was designed to determine the relationship betwe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ntemgwa, Michel, Wainberg, Mark A., Oliveira, Maureen, Moisi, Daniela, Lalonde, Richard, Micheli, Valeria, Brenner, Bluma G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2007
Gaiak:
Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151428/
https://ncbi.nlm.nih.gov/pubmed/17724152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00646-07
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