Differential Maintenance of the M184V Substitution in the Reverse Transcriptase of Human Immunodeficiency Virus Type 1 by Various Nucleoside Antiretroviral Agents in Tissue Culture

The M184V substitution in human immunodeficiency virus type 1 reverse transcriptase (RT) is rapidly selected in tissue culture following serial passage of wild-type virus in the presence of increasing concentrations of lamivudine (3TC). M184V is also associated with several alterations of RT enzymat...

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Detalhes bibliográficos
Main Authors: Petrella, Marco, Oliveira, Maureen, Moisi, Daniela, Detorio, Mervi, Brenner, Bluma G., Wainberg, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525456/
https://ncbi.nlm.nih.gov/pubmed/15504840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.11.4189-4194.2004
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