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Prediction of the 3D structure of rat MrgA G protein-coupled receptor and identification of its binding site

Mrg receptors are orphan G protein-coupled receptors (GPCRs) located mainly at the specific set of sensory neurons in the dorsal root ganglia, suggesting a role in nociception. We report here the 3-D structure of rat MrgA (rMrgA) receptor [obtained from homology modeling to the recently validated pr...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Heo, Jiyoung, Vaidehi, Nagarajan, Wendel, John, Goddard, William A.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151207/
https://ncbi.nlm.nih.gov/pubmed/17728165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2007.07.003
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