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Predicted 3D structure for the human β2 adrenergic receptor and its binding site for agonists and antagonists
We report the 3D structure of human β2 adrenergic receptor (AR) predicted by using the MembStruk first principles method. To validate this structure, we use the HierDock first principles method to predict the ligand-binding sites for epinephrine and norepinephrine and for eight other ligands, includ...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC365690/ https://ncbi.nlm.nih.gov/pubmed/14981238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308751101 |
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