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Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Gα(q/11) pathway

MrgA1 and MrgC11 belong to a recently identified family of orphan G-protein coupled receptors, called mrgs (mas-related genes). They are only expressed in a specific subset of sensory neurons that are known to detect painful stimuli. However, the precise physiological function of Mrg receptors and t...

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Detalhes bibliográficos
Main Authors: Han, Sang-Kyou, Dong, Xinzhong, Hwang, Jong-Ik, Zylka, Mark J., Anderson, David J., Simon, Melvin I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC137489/
https://ncbi.nlm.nih.gov/pubmed/12397184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192565799
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