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Axin and GSK3-β control Smad3 protein stability and modulate TGF-β signaling

The broad range of biological responses elicited by transforming growth factor-β (TGF-β) in various types of tissues and cells is mainly determined by the expression level and activity of the effector proteins Smad2 and Smad3. It is not fully understood how the baseline properties of Smad3 are regul...

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Detalhes bibliográficos
Main Authors: Guo, Xing, Ramirez, Alejandro, Waddell, David S., Li, Zhizhong, Liu, Xuedong, Wang, Xiao-Fan
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151009/
https://ncbi.nlm.nih.gov/pubmed/18172167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1590908
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