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Axin and GSK3-β control Smad3 protein stability and modulate TGF-β signaling

The broad range of biological responses elicited by transforming growth factor-β (TGF-β) in various types of tissues and cells is mainly determined by the expression level and activity of the effector proteins Smad2 and Smad3. It is not fully understood how the baseline properties of Smad3 are regul...

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Hlavní autoři: Guo, Xing, Ramirez, Alejandro, Waddell, David S., Li, Zhizhong, Liu, Xuedong, Wang, Xiao-Fan
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151009/
https://ncbi.nlm.nih.gov/pubmed/18172167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1590908
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