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Keratin attenuates tumor necrosis factor–induced cytotoxicity through association with TRADD
Keratin 8 and 18 (K8/18) are the major components of intermediate filament (IF) proteins of simple or single-layered epithelia. Recent data show that normal and malignant epithelial cells deficient in K8/18 are nearly 100 times more sensitive to tumor necrosis factor (TNF)–induced cell death. We hav...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2001
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2150850/ https://ncbi.nlm.nih.gov/pubmed/11684708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200103078 |
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