Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors

Tumor necrosis factor receptor 1-associated death domain protein (TRADD) is the core adaptor recruited to TNF receptor 1 (TNFR1) upon TNFα stimulation. In cells from TRADD-deficient mice, TNFα-mediated apoptosis and TNFα-stimulated NF-κB, JNK, and ERK activation are defective. TRADD is also importan...

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Detalhes bibliográficos
Main Authors: Chen, Nien-Jung, Chio, Iok In Christine, Lin, Wen-Jye, Duncan, Gordon, Chau, Hien, Katz, David, Huang, Huey-Lan, Pike, Kelly A., Hao, Zhenyue, Su, Yu-Wen, Yamamoto, Kazuo, de Pooter, Renée F., Zúñiga-Pflücker, Juan Carlos, Wakeham, Andrew, Yeh, Wen-Chen, Mak, Tak W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518828/
https://ncbi.nlm.nih.gov/pubmed/18719121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806585105
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