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The function of TRADD in signaling via tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors

The physiological role of the TRADD adaptor protein remains unclear due to the unavailability of a TRADD-deficient animal model. By generating TRADD-deficient mice, we demonstrated that TRADD plays a significant role in tumor necrosis factor receptor-1 (TNFR1) signaling by orchestrating the formatio...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Pobezinskaya, Yelena L., Kim, You-Sun, Choksi, Swati, Morgan, Michael J., Li, Tao, Liu, Chengyu, Liu, Zhenggang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577920/
https://ncbi.nlm.nih.gov/pubmed/18641653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1639
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