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The function of TRADD in signaling via tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors
The physiological role of the TRADD adaptor protein remains unclear due to the unavailability of a TRADD-deficient animal model. By generating TRADD-deficient mice, we demonstrated that TRADD plays a significant role in tumor necrosis factor receptor-1 (TNFR1) signaling by orchestrating the formatio...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2577920/ https://ncbi.nlm.nih.gov/pubmed/18641653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1639 |
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