Involvement of FKHR-Dependent TRADD Expression in Chemotherapeutic Drug-Induced Apoptosis

Chemotherapeutic drugs exhibit their cytotoxic effect by inducing apoptosis in tumor cells. Because the serine/threonine kinase Akt is involved in apoptosis suppression, we investigated the relationship between Akt activity and drug sensitivity. We discovered that certain chemotherapeutic drugs indu...

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Detalhes bibliográficos
Main Authors: Rokudai, Susumu, Fujita, Naoya, Kitahara, Osamu, Nakamura, Yusuke, Tsuruo, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139879/
https://ncbi.nlm.nih.gov/pubmed/12446787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.24.8695-8708.2002
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