IAP Suppression of Apoptosis Involves Distinct Mechanisms: the TAK1/JNK1 Signaling Cascade and Caspase Inhibition

The antiapoptotic properties of the inhibitor of apoptosis (IAP) family of proteins have been linked to caspase inhibition. We have previously described an alternative mechanism of XIAP inhibition of apoptosis that depends on the selective activation of JNK1. Here we report that two other members of...

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Bibliographic Details
Main Authors: Sanna, M. Germana, Correia, Jean da Silva, Ducrey, Odile, Lee, Jongdae, Nomoto, Ken, Schrantz, Nicolas, Deveraux, Quinn L., Ulevitch, Richard J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC135597/
https://ncbi.nlm.nih.gov/pubmed/11865055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.6.1754-1766.2002
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