IAP Suppression of Apoptosis Involves Distinct Mechanisms: the TAK1/JNK1 Signaling Cascade and Caspase Inhibition

The antiapoptotic properties of the inhibitor of apoptosis (IAP) family of proteins have been linked to caspase inhibition. We have previously described an alternative mechanism of XIAP inhibition of apoptosis that depends on the selective activation of JNK1. Here we report that two other members of...

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Detalhes bibliográficos
Main Authors: Sanna, M. Germana, Correia, Jean da Silva, Ducrey, Odile, Lee, Jongdae, Nomoto, Ken, Schrantz, Nicolas, Deveraux, Quinn L., Ulevitch, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135597/
https://ncbi.nlm.nih.gov/pubmed/11865055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.6.1754-1766.2002
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