The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases.

The inhibitor of apoptosis (IAP) family of proteins are highly conserved through evolution. However, the mechanisms by which these proteins interfere with apoptotic cell death have been enigmatic. Recently, we showed that one of the human IAP family proteins, XIAP, can bind to and potently inhibit s...

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Bibliographic Details
Main Authors: Roy, N, Deveraux, Q L, Takahashi, R, Salvesen, G S, Reed, J C
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170295/
https://ncbi.nlm.nih.gov/pubmed/9384571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.23.6914
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