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A20 Inhibits Tumor Necrosis Factor (TNF) Alpha-Induced Apoptosis by Disrupting Recruitment of TRADD and RIP to the TNF Receptor 1 Complex in Jurkat T Cells

Tumor necrosis factor receptor 1 (TNFR1) can trigger distinct signaling pathways leading to either the activation of NF-κB transcription factors or apoptosis. NF-κB activation results in the expression of antiapoptotic genes that inhibit the apoptosis pathway that is activated in parallel. However,...

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Autori principali: He, Kai-Li, Ting, Adrian T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC133997/
https://ncbi.nlm.nih.gov/pubmed/12167698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.17.6034-6045.2002
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