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TRADD mediates the tumor necrosis factor-induced apoptosis of L929 cells in the absence of RIP3
Receptor-interacting protein kinase 3 (RIP3) is a critical initiator in mediating necroptosis induced by tumor necrosis factor alpha (TNFα) in L929 cells, so knockdown of RIP3 inhibits TNFα-induced L929 cell necroptosis. However, RIP3 knockdown was shown to switch TNFα-induced necroptosis to apoptos...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5701027/ https://ncbi.nlm.nih.gov/pubmed/29170425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16390-6 |
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