TRADD mediates the tumor necrosis factor-induced apoptosis of L929 cells in the absence of RIP3

Receptor-interacting protein kinase 3 (RIP3) is a critical initiator in mediating necroptosis induced by tumor necrosis factor alpha (TNFα) in L929 cells, so knockdown of RIP3 inhibits TNFα-induced L929 cell necroptosis. However, RIP3 knockdown was shown to switch TNFα-induced necroptosis to apoptos...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Chang, Xixi, Wang, Lili, Wang, Zicheng, Wu, Shuai, Zhu, Xiaoming, Hu, Shiping, Wang, Yu, Yu, Jiyun, Chen, Guozhu
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701027/
https://ncbi.nlm.nih.gov/pubmed/29170425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16390-6
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