Keratin attenuates tumor necrosis factor–induced cytotoxicity through association with TRADD

Keratin 8 and 18 (K8/18) are the major components of intermediate filament (IF) proteins of simple or single-layered epithelia. Recent data show that normal and malignant epithelial cells deficient in K8/18 are nearly 100 times more sensitive to tumor necrosis factor (TNF)–induced cell death. We hav...

Full description

Saved in:
Bibliographic Details
Main Authors: Inada, Hiroyasu, Izawa, Ichiro, Nishizawa, Miwako, Fujita, Eriko, Kiyono, Tohru, Takahashi, Toshitada, Momoi, Takashi, Inagaki, Masaki
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2001
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150850/
https://ncbi.nlm.nih.gov/pubmed/11684708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200103078
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items