Inhibitors of poly (ADP-ribose) synthesis enhance radiation response by differentially affecting repair of potentially lethal versus sublethal damage.

The effect of nicotinamide and m-aminobenzamide, representative inhibitors of poly(ADP-ribose) synthesis, on the survival of V79 Chinese hamster cells following ionizing radiation was studied in plateau- and log-phase cultures. In plateau-phase, after an acute dose of X-rays, nicotinamide partially...

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Autores principales: Ben-Hur, E., Utsumi, H., Elkind, M. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1984
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149179/
https://ncbi.nlm.nih.gov/pubmed/6230094
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