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The influence of inhibitors of poly (ADP-ribose) polymerase on X-ray-induced potentially lethal damage repair.

Inhibition of repair of X-ray-induced potentially lethal damage (PLD) could enhance the curability of radioresistant tumours. We have studied the effect of inhibitors of the enzyme poly (ADP-ribose) polymerase on X-ray PLD repair. Four classes of inhibitors are known: aromatic amides (e.g., 3-aminob...

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Main Authors: Brown, D. M., Evans, J. W., Brown, J. M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1984
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2149166/
https://ncbi.nlm.nih.gov/pubmed/6320853
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