Profiling of UV-induced ATM/ATR signaling pathways

To ensure survival in the face of genomic insult, cells have evolved complex mechanisms to respond to DNA damage, termed the DNA damage checkpoint. The serine/threonine kinases ataxia telangiectasia-mutated (ATM) and ATM and Rad3-related (ATR) activate checkpoint signaling by phosphorylating substra...

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Hlavní autoři: Stokes, Matthew P., Rush, John, MacNeill, Joan, Ren, Jian Min, Sprott, Kam, Nardone, Julie, Yang, Vicky, Beausoleil, Sean A., Gygi, Steven P., Livingstone, Mark, Zhang, Hui, Polakiewicz, Roberto D., Comb, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148387/
https://ncbi.nlm.nih.gov/pubmed/18077418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707579104
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