Profiling of UV-induced ATM/ATR signaling pathways

To ensure survival in the face of genomic insult, cells have evolved complex mechanisms to respond to DNA damage, termed the DNA damage checkpoint. The serine/threonine kinases ataxia telangiectasia-mutated (ATM) and ATM and Rad3-related (ATR) activate checkpoint signaling by phosphorylating substra...

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Detalhes bibliográficos
Main Authors: Stokes, Matthew P., Rush, John, MacNeill, Joan, Ren, Jian Min, Sprott, Kam, Nardone, Julie, Yang, Vicky, Beausoleil, Sean A., Gygi, Steven P., Livingstone, Mark, Zhang, Hui, Polakiewicz, Roberto D., Comb, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148387/
https://ncbi.nlm.nih.gov/pubmed/18077418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707579104
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