Profiling of UV-induced ATM/ATR signaling pathways

To ensure survival in the face of genomic insult, cells have evolved complex mechanisms to respond to DNA damage, termed the DNA damage checkpoint. The serine/threonine kinases ataxia telangiectasia-mutated (ATM) and ATM and Rad3-related (ATR) activate checkpoint signaling by phosphorylating substra...

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Autors principals: Stokes, Matthew P., Rush, John, MacNeill, Joan, Ren, Jian Min, Sprott, Kam, Nardone, Julie, Yang, Vicky, Beausoleil, Sean A., Gygi, Steven P., Livingstone, Mark, Zhang, Hui, Polakiewicz, Roberto D., Comb, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148387/
https://ncbi.nlm.nih.gov/pubmed/18077418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707579104
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