Profiling of UV-induced ATM/ATR signaling pathways

To ensure survival in the face of genomic insult, cells have evolved complex mechanisms to respond to DNA damage, termed the DNA damage checkpoint. The serine/threonine kinases ataxia telangiectasia-mutated (ATM) and ATM and Rad3-related (ATR) activate checkpoint signaling by phosphorylating substra...

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Bibliographische Detailangaben
Hauptverfasser: Stokes, Matthew P., Rush, John, MacNeill, Joan, Ren, Jian Min, Sprott, Kam, Nardone, Julie, Yang, Vicky, Beausoleil, Sean A., Gygi, Steven P., Livingstone, Mark, Zhang, Hui, Polakiewicz, Roberto D., Comb, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148387/
https://ncbi.nlm.nih.gov/pubmed/18077418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707579104
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