Signaling networks assembled by oncogenic EGFR and c-Met

A major question regarding the sensitivity of solid tumors to targeted kinase inhibitors is why some tumors respond and others do not. The observation that many tumors express EGF receptor (EGFR), yet only a small subset with EGFR-activating mutations respond clinically to EGFR inhibitors (EGFRIs),...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Guo, Ailan, Villén, Judit, Kornhauser, Jon, Lee, Kimberly A., Stokes, Matthew P., Rikova, Klarisa, Possemato, Anthony, Nardone, Julie, Innocenti, Gregory, Wetzel, Randall, Wang, Yi, MacNeill, Joan, Mitchell, Jeffrey, Gygi, Steven P., Rush, John, Polakiewicz, Roberto D., Comb, Michael J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2008
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206598/
https://ncbi.nlm.nih.gov/pubmed/18180459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707270105
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