Signaling networks assembled by oncogenic EGFR and c-Met

A major question regarding the sensitivity of solid tumors to targeted kinase inhibitors is why some tumors respond and others do not. The observation that many tumors express EGF receptor (EGFR), yet only a small subset with EGFR-activating mutations respond clinically to EGFR inhibitors (EGFRIs),...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Guo, Ailan, Villén, Judit, Kornhauser, Jon, Lee, Kimberly A., Stokes, Matthew P., Rikova, Klarisa, Possemato, Anthony, Nardone, Julie, Innocenti, Gregory, Wetzel, Randall, Wang, Yi, MacNeill, Joan, Mitchell, Jeffrey, Gygi, Steven P., Rush, John, Polakiewicz, Roberto D., Comb, Michael J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2008
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206598/
https://ncbi.nlm.nih.gov/pubmed/18180459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707270105
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы