Hyperpolarized (13)C allows a direct measure of flux through a single enzyme-catalyzed step by NMR

(13)C NMR is a powerful tool for monitoring metabolic fluxes in vivo. The recent availability of automated dynamic nuclear polarization equipment for hyperpolarizing (13)C nuclei now offers the potential to measure metabolic fluxes through select enzyme-catalyzed steps with substantially improved se...

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Autori principali: Merritt, Matthew E., Harrison, Crystal, Storey, Charles, Jeffrey, F. Mark, Sherry, A. Dean, Malloy, Craig R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148374/
https://ncbi.nlm.nih.gov/pubmed/18056642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706235104
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