Hyperpolarized (13)C allows a direct measure of flux through a single enzyme-catalyzed step by NMR

(13)C NMR is a powerful tool for monitoring metabolic fluxes in vivo. The recent availability of automated dynamic nuclear polarization equipment for hyperpolarizing (13)C nuclei now offers the potential to measure metabolic fluxes through select enzyme-catalyzed steps with substantially improved se...

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Main Authors: Merritt, Matthew E., Harrison, Crystal, Storey, Charles, Jeffrey, F. Mark, Sherry, A. Dean, Malloy, Craig R.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2007
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148374/
https://ncbi.nlm.nih.gov/pubmed/18056642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706235104
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