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Hyperpolarized (13)C allows a direct measure of flux through a single enzyme-catalyzed step by NMR

(13)C NMR is a powerful tool for monitoring metabolic fluxes in vivo. The recent availability of automated dynamic nuclear polarization equipment for hyperpolarizing (13)C nuclei now offers the potential to measure metabolic fluxes through select enzyme-catalyzed steps with substantially improved se...

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Detalhes bibliográficos
Main Authors: Merritt, Matthew E., Harrison, Crystal, Storey, Charles, Jeffrey, F. Mark, Sherry, A. Dean, Malloy, Craig R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148374/
https://ncbi.nlm.nih.gov/pubmed/18056642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706235104
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