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A biochemical approach to identifying microRNA targets
Identifying the downstream targets of microRNAs (miRNAs) is essential to understanding cellular regulatory networks. We devised a direct biochemical method for miRNA target discovery that combined RNA-induced silencing complex (RISC) purification with microarray analysis of bound mRNAs. Because targ...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2148283/ https://ncbi.nlm.nih.gov/pubmed/18042700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709971104 |
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