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An alternative mode of microRNA target recognition

MicroRNAs (miRNAs) regulate mRNA targets through perfect pairing with their seed region (position 2-7). Recently, a precise genome-wide map of miRNA interaction sites in mouse brain was generated by high-throughput sequencing of clusters of ~50 nucleotide RNA tags associated with Argonaute (Ago HITS...

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Hlavní autoři: Chi, Sung Wook, Hannon, Gregory J., Darnell, Robert B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541676/
https://ncbi.nlm.nih.gov/pubmed/22343717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2230
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