Structural and functional consequences of the presence of a fourth disulfide bridge in the scorpion short toxins: solution structure of the potassium channel inhibitor HsTX1.

We have determined the three-dimensional structure of the potassium channel inhibitor HsTX1, using nuclear magnetic resonance and molecular modeling. This protein belongs to the scorpion short toxin family, which essentially contains potassium channel blockers of 29 to 39 amino acids and three disul...

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Detalhes bibliográficos
Main Authors: Savarin, P., Romi-Lebrun, R., Zinn-Justin, S., Lebrun, B., Nakajima, T., Gilquin, B., Menez, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144240/
https://ncbi.nlm.nih.gov/pubmed/10631983
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