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Solution structure of Pi4, a short four-disulfide-bridged scorpion toxin specific of potassium channels

Pi4 is a short toxin found at very low abundance in the venom of Pandinus imperator scorpions. It is a potent blocker of K(+) channels. Like the other members of the α-KTX6 subfamily to which it belongs, it is cross-linked by four disulfide bonds. The synthetic analog (sPi4) and the natural toxin (n...

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Autors principals: Guijarro, J. Iñaki, M’Barek, Sarrah, Gómez-Lagunas, Froylan, Garnier, Damien, Rochat, Hervé, Sabatier, Jean-Marc, Possani, Lourrival D., Delepierre, Muriel
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323982/
https://ncbi.nlm.nih.gov/pubmed/12930984
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