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Morphine-activated opioid receptors elude desensitization by β-arrestin

μ opioid receptors are targets of native opioid peptides and addictive analgesic drugs. A major clinical liability of opiate drugs is their ability to cause physiological tolerance. Individual opiates, such as morphine and etorphine, differ both in their ability to promote physiological tolerance an...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Whistler, Jennifer L., von Zastrow, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21436/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9707575/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.17.9914
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