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Anti-inflammatory properties of the μ opioid receptor support its use in the treatment of colon inflammation

The physiologic role of the μ opioid receptor (MOR) in gut nociception, motility, and secretion is well established. To evaluate whether MOR may also be involved in controlling gut inflammation, we first showed that subcutaneous administration of selective peripheral MOR agonists, named DALDA and DA...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Philippe, David, Dubuquoy, Laurent, Groux, Hervé, Brun, Valérie, Chuoï-Mariot, Myriam Tran Van, Gaveriaux-Ruff, Claire, Colombel, Jean-Frédéric, Kieffer, Brigitte L., Desreumaux, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154442/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12727924/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI16750
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