Microglia Express Mu Opioid Receptor: Insights From Transcriptomics and Fluorescent Reporter Mice
Background: Microglia activation contributes to chronic pain and to the adverse effects of opiate use such as analgesic tolerance and opioid-induced hyperalgesia. Both mu opioid receptor (MOR) encoded by Oprm1/OPRM1 gene and toll like receptor 4 (TLR4) have been reported to mediate these morphine ef...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2019-01-01
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| Serija: | Frontiers in Psychiatry |
| Teme: | |
| Online pristup: | https://www.frontiersin.org/article/10.3389/fpsyt.2018.00726/full |
| Oznake: |
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