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Morphine-activated opioid receptors elude desensitization by β-arrestin

μ opioid receptors are targets of native opioid peptides and addictive analgesic drugs. A major clinical liability of opiate drugs is their ability to cause physiological tolerance. Individual opiates, such as morphine and etorphine, differ both in their ability to promote physiological tolerance an...

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Hlavní autoři: Whistler, Jennifer L., von Zastrow, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1998
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC21436/
https://ncbi.nlm.nih.gov/pubmed/9707575
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