Morphine-activated opioid receptors elude desensitization by β-arrestin
μ opioid receptors are targets of native opioid peptides and addictive analgesic drugs. A major clinical liability of opiate drugs is their ability to cause physiological tolerance. Individual opiates, such as morphine and etorphine, differ both in their ability to promote physiological tolerance an...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1998
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21436/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9707575/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.17.9914 |
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