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Activated Phosphatidylinositol 3-Kinase and Akt Kinase Promote Survival of Superior Cervical Neurons

The signaling pathways that mediate the ability of NGF to support survival of dependent neurons are not yet completely clear. However previous work has shown that the c-Jun pathway is activated after NGF withdrawal, and blocking this pathway blocks neuronal cell death. In this paper we show that ove...

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Autori principali: Philpott, Karen L., McCarthy, Mary Jane, Klippel, Anke, Rubin, Lee L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141707/
https://ncbi.nlm.nih.gov/pubmed/9348296
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