A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

類似資料

• Expression of Phosphatidylinositol (4,5) Bisphosphate–specific Pleckstrin Homology Domains Alters Direction But Not the Level of Axonal Transport of Mitochondria
  著者:: De Vos, Kurt J., 等
  出版事項: (2003)
• Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors
  著者:: Barnett, Stanley F., 等
  出版事項: (2005)
• Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase
  著者:: August, Avery, 等
  出版事項: (1997)
• The Pleckstrin Homology Domain of Diacylglycerol Kinase η Strongly and Selectively Binds to Phosphatidylinositol 4,5-Bisphosphate
  著者:: Kume, Aiko, 等
  出版事項: (2016)
• Pleckstrin Homology Domain of Akt Kinase: A Proof of Principle for Highly Specific and Effective Non-Enzymatic Anti-Cancer Target
  著者:: Joh, Eun-Ha, 等
  出版事項: (2012)