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Depolarization and Neurotrophins Converge on the Phosphatidylinositol 3-Kinase–Akt Pathway to Synergistically Regulate Neuronal Survival

In this report, we have examined the mechanisms whereby neurotrophins and neural activity coordinately regulate neuronal survival, focussing on sympathetic neurons, which require target-derived NGF and neural activity for survival during development. When sympathetic neurons were maintained in subop...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vaillant, A.R., Mazzoni, I., Tudan, C., Boudreau, M., Kaplan, D.R., Miller, F.D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169479/
https://ncbi.nlm.nih.gov/pubmed/10477751
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