Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

We have found that insulin-like growth factor I (IGF-I) can protect fibroblasts from apoptosis induced by UV-B light. Antiapoptotic signalling by the IGF-I receptor depended on receptor kinase activity, as cells overexpressing kinase-defective receptor mutants could not be protected by IGF-I. Overex...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Mol Cell Biol
Päätekijät:	Kulik, G, Klippel, A, Weber, M J
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Taylor & Francis 1997
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231885/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032287/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.3.1595
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