Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

We have found that insulin-like growth factor I (IGF-I) can protect fibroblasts from apoptosis induced by UV-B light. Antiapoptotic signalling by the IGF-I receptor depended on receptor kinase activity, as cells overexpressing kinase-defective receptor mutants could not be protected by IGF-I. Overex...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Kulik, G, Klippel, A, Weber, M J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC231885/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9032287/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.17.3.1595
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!