Bim mediates mitochondria-regulated particulate matter-induced apoptosis in alveolar epithelial cells

We studied the role of Bim, a pro-apoptotic BCL-2 family member in Airborne particulate matter (PM 2.5 μm)-induced apoptosis in alveolar epithelial cells (AEC). PM induced AEC apoptosis by causing significant reduction of mitochondrial membrane potential and increase in caspase-9, caspase-3 and PARP...

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Huvudupphovsmän: Zhang, J., Ghio, A.J., Chang, W., Kamdar, O., Rosen, G.D., Upadhyay, D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140150/
https://ncbi.nlm.nih.gov/pubmed/17716672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.07.080
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