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AMBIENT PARTICULATE MATTER INDUCES ALVEOLAR EPITHELIAL CELL CYCLE ARREST: ROLE OF G1 CYCLINS
We hypothesized that the ambient air pollution particles (PM) induce cell cycle arrest in alveolar epithelial cells (AEC). Exposure of PM (25μg/cm(2)) to AEC induced cells cycle arrest in G1 phase, inhibited DNA synthesis, blocked cell proliferation and caused decrease in cyclin E, A, D1 and Cyclin...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2140149/ https://ncbi.nlm.nih.gov/pubmed/17977533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.10.020 |
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