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Requirement of the MRN complex for ATM activation by DNA damage
The ATM protein kinase is a primary activator of the cellular response to DNA double-strand breaks (DSBs). In response to DSBs, ATM is activated and phosphorylates key players in various branches of the DNA damage response network. ATM deficiency causes the genetic disorder ataxia-telangiectasia (A-...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC213795/ https://ncbi.nlm.nih.gov/pubmed/14532133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg541 |
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