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Recruitment of ATR to sites of ionising radiation-induced DNA damage requires ATM and components of the MRN protein complex
ATM and ATR are two related kinases essential for signalling DNA damage. Although ATM is thought to be the principle kinase responsible for signalling ionising radiation (IR)-induced DNA damage, ATR also contributes to signalling this form of genotoxic stress. However, the molecular basis of differe...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852851/ https://ncbi.nlm.nih.gov/pubmed/16474843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209426 |
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