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Condensin I recruitment and uneven chromatin condensation precede mitotic cell death in response to DNA damage

Mitotic cell death (MCD) is a prominent but poorly defined form of death that stems from aberrant mitosis. One of the early steps in MCD is premature mitosis and uneven chromatin condensation (UCC). The mechanism underlying this phenomenon is currently unknown. In this study, we show that DNA damage...

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Detalhes bibliográficos
Main Authors: Blank, Michael, Lerenthal, Yaniv, Mittelman, Leonid, Shiloh, Yosef
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064180/
https://ncbi.nlm.nih.gov/pubmed/16847100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200604022
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