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Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus

In vivo treatment of mice with the natural killer T (NKT) cell ligand, α-galactosylceramide (αGalCer), ameliorates autoimmune diabetes and experimental autoimmune encephalomyelitis (EAE) by shifting pathogenic Th1-type immune responses to nonpathogenic Th2-type responses. In the current study, in vi...

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Detalhes bibliográficos
Main Authors: Zeng, Defu, Liu, Yinping, Sidobre, Stephane, Kronenberg, Mitchell, Strober, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC213484/
https://ncbi.nlm.nih.gov/pubmed/14561706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317165
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