Cross-presentation of Disialoganglioside GD3 to Natural Killer T Cells

GD3, a ganglioside expressed on human melanoma, can be recognized by the humoral immune system. In this paper, we demonstrate that immunizing mice with the human melanoma cell line SK-MEL-28 (GD3(+) GM2(−) CD1(−)) or with syngeneic APCs loaded with GD3 can induce a GD3-reactive natural killer T (NKT...

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Bibliographic Details
Main Authors: Wu, Dianna Y., Segal, Neil H., Sidobre, Stephane, Kronenberg, Mitchell, Chapman, Paul B.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2003
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196074/
https://ncbi.nlm.nih.gov/pubmed/12847141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030446
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